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IPARGS
Institute for Advanced Research
IPARGS – the Institute for Advanced Research of Rio Grande do Sul – is a clinical research center whose objective is to provide infrastructure and technical support for studies in various health specialties. Initially, all research conducted by IPARGS focused on HIV/AIDS. However, the excellent results obtained in our area of study, as well as the work of our highly qualified multidisciplinary team, have expanded our scope to include other diseases.
IPARGS
Social Purpose
Learn about the principles that drive our actions and underpin our commitment to research and the health of society.
Conduct SCIENTIFIC RESEARCH in the area of infectious diseases (especially in phases II, III and IV).
Promoting EDUCATION and AWARENESS with a focus on prevention.
To promote the DEVELOPMENT and DISSEMINATION of scientific projects.
Create, develop, or support RESEARCH PROTOCOLS
IPARGS
Clinical Studies
Learn about the clinical studies currently underway at IPARGS and find out how you can contribute to the advancement of science. If you are interested in participating as a volunteer, your collaboration can make a difference in the health of many people.
Study
A5374
Study A5374 is a randomized, two-arm, double-blind, placebo-controlled, multi-stage Phase I/IIa clinical trial designed to evaluate the safety and efficacy of therapeutic vaccination with conserved mosaic T-cell vaccines vectored by chimpanzee adenovirus (ChAdV) and modified Ankara vaccinia poxvirus (MVA) in a sequential regimen...
Duration:
- weeks
Participants:
- pessoas
Study
A5384
A Phase II, Randomized, Open-Label Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Compared to a Standard Nine-Month Regimen for Treatment of Adults and Adolescents with Tuberculous Meningitis: Improved Management with Isoniazid Rifampicin Linezolid Antimicrobial Agents for TBM (IMAGINE-TBM).
Duration:
until 05/15/2028
Participants:
- people
Study
Codenchik
Phase 3b, Multicenter, Randomized, Controlled, Double-blind Clinical Trial to Evaluate the Immunogenicity and Safety of Co-administration of Live Attenuated Dengue and Chikungunya Vaccines Compared to Administration Alone in Adults Aged 18 to 59 Years.
Duration:
Jan 15, 2026 to May 01, 2026
Participants:
350 people
Study
A5389
A Phase I Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytical Treatment Interruption in Participants Living with HIV Who Initiated ART During Acute/Early HIV-1 Infection.
Duration:
Jan 01, 2026 to Dec 31, 2028
Participants:
- people
FAQs
Frequently Asked Questions
In this section, we answer the main questions about how a clinical trial works. Didn't find the answer you were looking for? Talk to our team.
1.
What is a clinical trial?
This refers to any investigation involving human participants, with the aim of discovering or verifying the pharmacodynamic, pharmacological, clinical and/or other effects of a product and/or identifying adverse reactions to the product(s) under investigation, in order to evaluate their safety and/or efficacy. However, in practice, the term is commonly used to refer to national or international multicenter studies, which may be experimental or observational, and are funded by the pharmaceutical industry, universities or governmental organizations. The execution of a clinical study is based on strict adherence to the rules described in the research protocol, which must be prepared in accordance with international standards that guarantee its proper conduct, according to ethical, scientific and patient-respect standards.
2.
Why participate?
Participants in a clinical trial have the opportunity to receive new treatments even before they are available on the market. Through the IPARGS team, participants receive free support and detailed health monitoring throughout the study, with rigorous and careful follow-up.
3.
Who can participate?
To take part in a clinical study, volunteers must meet the specific eligibility requirements of each research protocol. Inclusion and exclusion criteria are used to correctly identify participants and ensure their safety. These criteria are based on factors such as age, gender, type and stage of the disease, history of previous treatments, and other medical conditions.
4.
How does patient recruitment occur, and what is informed consent?
It is the process by which a patient voluntarily confirms their willingness to participate in a study after being informed about all aspects of the research relevant to that decision. To help someone decide whether or not to participate, members of the research team explain details about the research, such as its purpose, duration, necessary procedures, contact persons, risks, and potential benefits.
Next, the team provides a document containing these detailed explanations, called the Free and Informed Consent Form (TCLE), which is available in the downloads section of this website. Informed consent is then documented through the TCLE, signed and dated by the patient (or their legal representative) and the person who obtained the consent (a member of the research team).
5.
What is a protocol?
A protocol is a document that describes the objectives of a study, the types of eligible participants, the methodology, the testing schedule, procedures, medications and dosages, as well as the duration of the study. Its main purpose is to protect the health of the participants and answer specific research questions. Only through the rigorous execution of this control and monitoring is it possible to determine and properly apply the safety and efficacy of the treatment.
6.
What is a placebo?
A placebo is a pill, liquid, or powder made to resemble a real medication but has no therapeutic value. In clinical studies, experimental treatments are often compared to placebos to assess their effectiveness by observing the patient's condition with and without the medication. In some studies, participants in the control group receive a placebo instead of the active medication or treatment.
7.
What is a control group?
A control group serves as a standard for evaluating experimental observations. In many clinical studies, the experimental drug or treatment is administered to one group of patients, while the control group receives the standard treatment for the disease or a placebo. The control group is essential for research because it establishes what the patient's normal condition would be without the experimental treatment.
CCA-RS
Community Advisory Committee
The Community Advisory Committee (CCA-RS), established in 2000, is a committee composed of volunteers. Its members are individuals from the community, regardless of their area of expertise. Research participants themselves may also be included, provided they are informed about the existence of the committee and have the option to become members. The committee plays an advisory and monitoring role in clinical research, aiming to foster dialogue between the community and researchers.
Social Media
News
Follow our Instagram profile to stay up-to-date on all the latest news, new projects, ongoing clinical trials, and content about clinical health research.
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